Nfl Rushing Yards Record 2025 Record. Between this season and the 2025 season, derrick henry rushed for the most yards, with 1,120 yards. Between this season and the 2025 season, derrick henry rushed for the most yards, with 1,185 yards.

+ indicates hall of famer, season age in parentheses Peterson owns the record for the most rushing yards in a game with 296.